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NINJ Using New Liquid Treatment for Brain Aneurysms
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  • 10-22-2010

 

NINJ Using New Liquid Treatment for Brain Aneurysms

 

Newark, NJ. – October 20, 2010 –The NINJ announced today that Drs. Chirag D. Gandhi and Charles J. Prestigiacomo, both cerebrovascular & endovascular neurosurgeons will begin using an FDA-approved liquid system for treating wide-necked brain aneurysms.

 

Drs. Gandhi and Prestigiacomo are two of the few physicians now trained nationwide to use this novel product for the treatment of aneurysms. A brain aneurysm is a weakness in a major blood vessel that causes a portion of the vessel wall to balloon out. This abnormality puts an individual at risk should the aneurysm break open and bleed.

 

“A wide-necked brain aneurysm occurs in about 25 percent of patients with brain aneurysms,” said Dr. Gandhi “Wide-necked aneurysms can be difficult to treat surgically, which requires removal of bone and manipulation of the brain.  However, by using the liquid treatment called Onyx HD-500, we are able to use a minimally invasive endovascular procedure to treat the aneurysm from within the blood vessel.” 

 

To date, there have been no research studies conducted to show whether this liquid system is effective for treating wide-neck aneurysms, but clinical results are encouraging.   Dr. Gandhi continued, “The potential benefit of the liquid embolic system may be the complete blockage of the blood supply to the aneurysm.  This would make a recurrence of the aneurysm less likely than seen with current treatment methods.  It may also help to correct or lessen some symptoms.”

 

Typically, the surgeon will navigate a small catheter from the groin to the brain aneurysm and fill the aneurysm with metallic coils, causing clotting of the aneurysm.  However, there is the possibility that the clot may dissolve, resulting in a recurrence of the aneurysm.  In addition, some wide-necked aneurysms have such a large opening that the coils may not stay inside the aneurysm sac.  By filling the aneurysm sac or pocket with the Onyx liquid, which solidifies in approximately five minutes, blood flow into the aneurysm is blocked, helping to prevent the aneurysm from rupturing or increasing in size.

 

The Onyx liquid treatment has been FDA approved under a Humanitarian Device Exemption from the U.S. Food & Drug Administration, which allows physicians to use the liquid to treat a disease or condition that affects fewer than 4,000 individuals in the United States per year and for which no comparable device is available.  To qualify for treatment, patients must possess intracranial, saccular, sidewall aneurysms that present with a wide neck (≥ 4 mm) or with a dome-to-neck ratio < 2 that are not amenable to treatment with surgical clipping.

 

More information on brain aneurysms can be found at the following Web sites:

The National Institute of Neurological Disorders and Stroke (NINDS)http://www.ninds.nih.gov

 

American Stroke Association http://www.strokeassociation.org